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Cardiology

The cardiology group is mainly focusing on haemodynamic changes during exercise in children and adolescents; normal and with congenital heart defects.

We are also evaluating myocardial function and perfusion by MRI and echocardiography both in the foetal heart just before and after birth and in selected groups of patients with congenital heart defects like tetralogy of Fallot, transposition of the great arteries and coarctation of the aorta.

Ongoing studies often include evaluation of endothelial function measured by ischaemic induced hyperperfusion in brachial artery and intima thickness in the carotid arteries.

Leader of this group:

Prof. Dr.med. Gottfried Greve

Members of the group have a wide range of collaboration especially in epidemiological studies in the prevalence of congenital heart disease, recurrence risk, and risk factors for congenital heart defects.

We have been one of the main participants in the REDUCE study on closure of persistent foramen ovale in patients with cryptogenic cerebral strokes, and are collaborating in a studies of oral health in children with congenital heart defects, and cardiac risk factors in persons born prematurely.

We are also participating in the Nordic study of patients operated with atrial switch (a.m. Senning and Mustard) for transposition of the great arteries.

We also have a tradition with evaluation of clinical procedures and methods at the present of blood pressure measurements in children.

Our projects in:

Peadiatric cardiology

Our group is p.t. focusing within the following three main fields of research:

1

Myocardial function and endothelial function, as measured by ultrasound, in health children and children with congenital heart defects

At the present we are focusing on the changes occurring just before and after birth in Collaboration with Dr. PhD, Jörg Kessler and Dr. PhD, Cathrine Ebbing at Department of Obstetric and Gynaecology.

In late follow up of premature born young adults in collaboration with Professor Thomas Halvorsen. Cardiac function and coronary flow reserve are also studied by cardiac MRI in collaboration with Professor Terje H. Larsen, Department of Biomedicine

Project team:

Dr. Tom R. Omdal

Dr. Britt Engan

Dr. Katja Stein

Engineer Stig Samnøy

Dr. PhD, Elisabeth Lerigul

Prof. Dr.med. Ansgar Berg

Prof. Dr.med. Gottfried Greve

2

Registry based research in collaboration Professor Nina Øyen at Department of Global Public Health and Primary Care

Within the frame of CVDNOR (https://cvdnor.w.uib.no) we have looked on the prevalence of congenital heart defects, risk factors like maternal diabetes and folic acid supplement as well as the association with Down syndrome and preeclampsia and sibling recurrence. 

Project team:

Dr. PhD, Elisabeth Lerigul

Dr. Kristoffer Brodwall

Prof. Dr.med. Gottfried Greve

3

Exercise physiology during childhood and adolescents and the quality measurements collected during exercise and during a day

At the present we are focusing on altered physical performance during puberty, and diurnal blood pressure regulation. The studies are all carried out in The Energy Centre for Children and Adolescents (https://helse-bergen.no/om-oss/vi-bygger-nytt-sjukehus/barne-og-ungdomssjukehuset-bus) .

Project team:

Dr. PhD Asle Hirth

Prof. Dr.med. Ansgar Berg

RN Erlend B Johnsen

Prof. Dr.med. Gottfried Greve

Members of the cardio group

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Prof. Dr.med. Ansgar Berg

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MD, PhD Asle Hirt

RN Erlend B Johnsen

MD, PhD Elisabeth Leirgul

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MD Tom Omdal

MD Britt Engan

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MD, PhD Kristoffer Brodwall