Projects on Physical Activity
1. PEP - Follow up on those born extremely premature
During the last 3 to 4 decades long-term survival of those born extremely preterm has increased considerably. All organ systems are immature and vulnerable when born extremely preterm (EPB), and most of these infants require advanced intensive care treatment. Paradoxically, treatment measures required to save their lives in the short-term may also be potentially harmful in the long-term.
The full consequences of this remain unknown. Repeated studies over decades are needed to address these continuously evolving changes.
In Bergen, we have studied long-term outcomes in several consecutive population-based cohorts of extremely preterm born (EPB) subjects and matched term-born (TB) controls.
Our previous studies showed that those born extremely preterm have lower oxygen consumption than those born at term, and that this may be partly explained by lower physical activity. Physical activity is important for good health and reducing risk of diseases. Because those born premature also have a higher risk of cardiovascular disease, it is of importance to study this aspect.
The regional ethical committee for medical research has approved new examinations of the regional groups born extremely preterm or at extremely low birthweight, alongside termborn control subjects born in 1982-85, 1991-92 and 1999-2000. A new treadmill test will give us valuable information on health condition in general, and tell us if those born premature follow the same decline in physical capacity as those born at term when aging. We depend on a high participation rate to gain valid statistical results, and sincerely hope that our participants will take time to answer both questionnaires and to perform clinical examinations!
Doctorates or Ph.D dissertations emerging from the respiratory group:
Hege Havstad Clemm. Exercise Capacity after extremely preterm birth. Development from childhood to adulthood. University of Bergen 2015.
Ola Drange Røksund. Larynx in exercising humans. The unexplored bottleneck of the airways. University of Bergen 2012.
Mette Engan, Physical Capacity in young adults born extremely preterm - ongoing