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Mother and Baby

Project Extreme Prematurity (PEP)

Includes those born before 28 weeks of gestational age or under 1000g in the Western part of Norway.

Leader of this group:

Prof. MD Thomas Halvorsen


The purpose of PEP

The purpose of PEP is to study short- and long-term health and well-being in children born extremely prematurely. 

Such knowledge is needed to improve treatment in pregnancy, in the neonatal period and later, and could be used to better facilitate optimal outcomes for the children and their families through life.


Our follow-up cohorts​

The follow-ups have been ongoing since 2018 with a participation rate more than 70%.

Western Norway follow-up

Conducted in 2017-2018

Includes the cohorts:

PEP 1982 - 1985    at approximately 35 years of age

PEP 1991 - 1992    at approximately 27 years of age

PEP 1999 - 2000    at approximately 19 years of age

The knowledge this study has given us contributes to the world's understanding of the long-term consequences of newborn intensive care medicine and how premature children develop later in life.


National follow-up

Conducted in 2017-2018

Includes the cohort:

PEP 2010 - 2018 (Baby PEP)    at approximately 27 years of age

We follow all children born in Norway in 1999-2000 with a gestational age lower than 28 weeks or a birth weight lower than 1000 gram.

We have included comprehensive information, clinical and questionnaire-based, on the children from their pregnancy, the neonatal period and from 2, 5 and 11 years of age.


Involved research groups

The following groups will all be part of this follow-up:

Prematurity in media

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